1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
機能Catalyzes the formation of ganglioside GM3 (alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide).
組織特異性Ubiquitous. High expression in brain, skeletal muscle, placenta, and testis.
関連疾患Defects in ST3GAL5 are the cause of Amish infantile epilepsy syndrome (AIES) [MIM:609056]. AIES is an autosomal recessive, infantile-onset symptomatic epilepsy associated with developmental stagnation and blindness.
配列類似性Belongs to the glycosyltransferase 29 family.
Immunohistochemistry analysis in formalin fixed and paraffin embedded Human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. ab107534 at a dilution of 1/50.
Anti-ST3GAL5 antibody (ab107534) 使用論文
has not yet been referenced specifically in any publications.