Anti-ST3GAL2 抗体 (ab96028)
Key features and details
- Rabbit polyclonal to ST3GAL2
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-ST3GAL2 antibody
ST3GAL2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to ST3GAL2 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 68 and 297 of Human ST3GAL2 (UniProt ID: Q16842).
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ポジティブ・コントロール
- 293T, A431, HeLaS3, HepG2, MOLT4, Raji and H1299 whole cell lysates
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96028の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 40 kDa. |
ターゲット情報
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機能
It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. -
組織特異性
Highly expressed in skeletal muscle and heart and to a much lesser extent in brain, placenta, liver and pancreas. Scarcely detectable in lung and kidney. -
パスウェイ
Protein modification; protein glycosylation. -
配列類似性
Belongs to the glycosyltransferase 29 family. -
翻訳後修飾
The soluble form derives from the membrane form by proteolytic processing. -
細胞内局在
Golgi apparatus > Golgi stack membrane. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. - Information by UniProt
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参照データベース
- Entrez Gene: 6483 Human
- Entrez Gene: 20444 Mouse
- Entrez Gene: 64442 Rat
- Omim: 607188 Human
- SwissProt: Q16842 Human
- SwissProt: Q11204 Mouse
- SwissProt: Q11205 Rat
- Unigene: 368611 Human
see all -
別名
- 3-GalNAc-alpha-2 antibody
- 3-sialyltransferase 2 antibody
- 3-sialyltransferase antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab96028 は 2 報の論文で使用されています。
- Li Y et al. Alpha-2, 3-sialyltransferases regulate the multidrug resistance of chronic myeloid leukemia through miR-4701-5p targeting ST3GAL1. Lab Invest 96:731-40 (2016). PubMed: 27088512
- Ali MF et al. Golgi Phosphoprotein 3 Determines Cell Binding Properties under Dynamic Flow by Controlling Golgi Localization of Core 2 N-Acetylglucosaminyltransferase 1. J Biol Chem 287:39564-77 (2012). ICC/IF . PubMed: 23027862