製品の概要

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab48571 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/312500.
WB Use a concentration of 0.5 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 21 kDa).Can be blocked with SSX2 peptide (ab182921). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Could act as a modulator of transcription.
  • 組織特異性Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
  • 関連疾患Note=A chromosomal aberration involving SSX2 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • 配列類似性Belongs to the SSX family.
    Contains 1 KRAB-related domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cancer/testis antigen 5.2 antibody
    • Cancer/testis antigen family 5, member 2a antibody
    • Cancer/testis antigen family 5, member 2b antibody
    • CT5.2 antibody
    • CT5.2A antibody
    • CT5.2b antibody
    • HD21 antibody
    • hom mel 40 antibody
    • HOM-MEL-40 antibody
    • MGC119055 antibody
    • MGC15364 antibody
    • MGC3884 antibody
    • Protein SSX2 antibody
    • RP11-552J9.2 antibody
    • sarcoma, synovial, X-chromosome related 2 antibody
    • SSx antibody
    • SSX2 antibody
    • SSX2-SYT fusion gene, included antibody
    • SSX2_HUMAN antibody
    • SSX2B antibody
    • Synovial sarcoma antibody
    • synovial sarcoma X breakpoint 2 antibody
    • Synovial sarcoma, X breakpoint 2B antibody
    • Tumor antigen HOM-MEL-40 antibody
    • X breakpoint 2 antibody
    see all

Anti-SSX2 antibody 画像

  • Anti-SSX2 antibody (ab48571) at 0.5 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 21 kDa
    Observed band size : 21 kDa

Anti-SSX2 antibody (ab48571) 使用論文

ab48571 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab48571.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"