製品の概要

  • 製品名Anti-SS18 antibody
    SS18 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SS18
  • 特異性ab66013 detects endogenous levels of total SS18 protein.
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from N terminus of human SS18.

  • ポジティブ・コントロール
    • Extracts from HepG2 cells, COLO205 cells and Jurkat cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab66013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/5000.
WB 1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 42 kDa).

ターゲット情報

  • 機能Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation.
  • 組織特異性Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
  • 関連疾患Note=A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • 配列類似性Belongs to the SS18 family.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC116875 antibody
    • Protein SSXT antibody
    • Protein SYT antibody
    • SS18 antibody
    • SSXT antibody
    • SSXT/SSX4v fusion antibody
    • SSXT_HUMAN antibody
    • Synovial sarcoma translocated to X chromosome antibody
    • Synovial sarcoma translocated to X chromosome protein antibody
    • Synovial sarcoma translocation chromosome 18 antibody
    • SYT antibody
    • SYT SSX1 antibody
    • SYT SSX2 antibody
    • SYT/SSX4v fusion protein antibody
    • SYTSSX1 antibody
    • SYTSSX2 antibody
    see all

Anti-SS18 antibody 画像

  • All lanes : Anti-SS18 antibody (ab66013) at 1/500 dilution

    Lane 1 : HepG2 cell extracts
    Lane 2 : COLO205 cell extracts
    Lane 3 : Jurkat cell extracts
    Lane 4 : Jurkat cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 42 kDa
    Observed band size : 44 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 120 kDa,30 kDa,80 kDa. We are unsure as to the identity of these extra bands.

Anti-SS18 antibody (ab66013) 使用論文

ab66013 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab66013.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"