Anti-SRXN1 抗体 (ab92298)
Key features and details
- Goat polyclonal to SRXN1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SRXN1 antibody
SRXN1 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to SRXN1 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- Human colon and kidney lysates
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab92298 is purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab92298の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB | (4) |
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 14 kDa).
1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 14 kDa). 1 hour primary incubation is recommended for this product. |
ターゲット情報
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関連性
SRXN1 contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. It does not act on PRDX5 or PRDX6. SRXN1 may catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. -
細胞内局在
Cytoplasmic -
参照データベース
- Entrez Gene: 140809 Human
- Entrez Gene: 296271 Rat
- SwissProt: Q9BYN0 Human
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別名
- C20orf1392 antibody
- Chromosome 20 open reading frame 139 antibody
- dJ850E9.2 antibody
see all
画像
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Anti-SRXN1 antibody (ab92298) at 0.5 µg/ml + Human Kidney lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 14 kDa
Observed band size: 16 kDa why is the actual band size different from the predicted?
Primary incubation was 1 hour.
データシートおよび資料
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Datasheet download
参考文献 (3)
ab92298 は 3 報の論文で使用されています。
- He J et al. Sulfiredoxin-1 attenuates injury and inflammation in acute pancreatitis through the ROS/ER stress/Cathepsin B axis. Cell Death Dis 12:626 (2021). PubMed: 34140464
- Barquilha CN et al. Sulfiredoxin as a Potential Therapeutic Target for Advanced and Metastatic Prostate Cancer. Oxid Med Cell Longev 2020:2148562 (2020). PubMed: 32411320
- Trstenjak Prebanda M et al. Upregulation of Mitochondrial Redox Sensitive Proteins in LPS-Treated Stefin B-Deficient Macrophages. Cells 8:N/A (2019). PubMed: 31766320