製品の概要

  • 製品名Anti-SRRM2 antibody
    SRRM2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SRRM2
  • アプリケーション適用あり: IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant Protein Epitope Signature Tag antigen, corresponding to amino acids 1098 - 1203 of Human SRRM2 Isoforms 1 and 2 (Q9UQ35). Note: this sequence is missing in Isoform 3.

  • ポジティブ・コントロール
    • Human liver tissue
      Human cell line U-2 OS

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーpH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab122719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100

ターゲット情報

  • 機能Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity). Binds to RNA.
  • 組織特異性Expressed in liver, placenta, and white blood cells.
  • 配列類似性Belongs to the CWC21 family.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus speckle.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 300 kDa nuclear matrix antigen antibody
    • CWC21 antibody
    • KIAA0324 antibody
    • Ser/Arg-related nuclear matrix protein of 300 kDa antibody
    • Serine/arginine repetitive matrix protein 2 antibody
    • Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa antibody
    • Splicing coactivator subunit SRm300 antibody
    • SR-related nuclear matrix protein of 300 kDa antibody
    • SRL300 antibody
    • SRM300 antibody
    • SRRM2 antibody
    • SRRM2_HUMAN antibody
    • Tax-responsive enhancer element-binding protein 803 antibody
    • TaxREB803 antibody
    see all

Anti-SRRM2 antibody 画像

  • ab122719, at a 1/500 dilution, staining SRRM2 in paraffin-embedded Human liver tissue by Immunohistochemistry.
  • ab122719, at 4 ug/ml, staining SRRM2 in Human cell line U-2 OS by Immunoflouroscence.

Anti-SRRM2 antibody (ab122719) 使用論文

This product has been referenced in:
  • Bai B  et al. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proc Natl Acad Sci U S A 110:16562-7 (2013). IHC-FrFl ; Human . Read more (PubMed: 24023061) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab122719.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"