製品の概要

  • 製品名
  • 製品の詳細
    Sheep polyclonal to SRPR beta
  • アプリケーション
    適用あり: WB, IPmore details
  • 種交差性
    交差種: Dog
  • 免疫原

    Synthetic peptide, corresponding to C terminal amino acids 246-265 of Dog SRPR beta.

  • ポジティブ・コントロール
    • Canine microsomal protein.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: 0.08% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 特記事項(精製)
    Purified by ammonium sulfate precipitation This antibody is provided as a 0.2 µm sterile filtered solution.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab16146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 30 kDa.
IP Use at an assay dependent dilution.

ターゲット情報

  • 機能
    Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.
  • 配列類似性
    Belongs to the SRP receptor beta subunit family.
  • 細胞内局在
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 別名
    • APMCF1 antibody
    • Protein APMCF1 antibody
    • Signal recognition particle receptor B subunit antibody
    • Signal recognition particle receptor beta subunit antibody
    • Signal recognition particle receptor subunit beta antibody
    • SR-beta antibody
    • SRbeta antibody
    • SRPR beta antibody
    • Srprb antibody
    • SRPRB_HUMAN antibody
    see all

画像

  • ab16146 detecting SRPR beta from canine microsomal protein by western blot Lane 1: 3ng of canine microsomal protein Lane 2: 6ng of canine microsomal protein Lane 3: 12ng of canine microsoaml protein

参考文献

This product has been referenced in:
  • Lakkaraju AK  et al. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation. Mol Biol Cell 23:2712-22 (2012). WB . Read more (PubMed: 22648169) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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