製品の概要

  • 製品名Anti-SRPK1 antibody
    SRPK1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SRPK1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: NETLRHKEDL HNANDCDVQN LNQESSFLSS QNGDSSTSQE TDSCTPITSE VSDTMVCQSS STVGQSFSEQ HISQLQESIR AEIPCEDEQE QEHNGPLDNK , corresponding to amino acids 371-470 of Human SRPK1

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab58003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.
    • 組織特異性Isoform 2 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 is only seen in the testis, at lower levels than isoform 2.
    • 配列類似性Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
      Contains 1 protein kinase domain.
    • 細胞内局在Cytoplasm. Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Serine/arginine rich protein specific kinase 1 antibody
      • Serine/arginine rich splicing factor kinase 1 antibody
      • Serine/arginine-rich protein-specific kinase 1 antibody
      • Serine/threonine protein kinase SRPK1 antibody
      • Serine/threonine-protein kinase SRPK1 antibody
      • SFRS protein kinase 1 antibody
      • SFRSK1 antibody
      • SR protein kinase 1 antibody
      • SR protein specific kinase 1 antibody
      • SR-protein-specific kinase 1 antibody
      • SRPK1 antibody
      • SRPK1_HUMAN antibody
      see all

    Anti-SRPK1 antibody 画像



    • Predicted band size : 92 kDa
      SRPK1 antibody (ab58003) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-SRPK1 antibody (ab58003) 使用論文

    ab58003 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab58003.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"