製品の概要
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製品名Anti-SRD5A2 antibody
SRD5A2 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to SRD5A2
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由来種Goat
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アプリケーション適用あり: WBmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse, Rat, Dog, Pig, Cynomolgus monkey
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免疫原
Synthetic peptide:
KMFEDYPKSRK
witn a cysteine residue linker, corresponding to C terminal amino acids 237-247 of SRD5A2 (NP_000339.2). -
ポジティブ･コントロール
- Human testis lysates
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 -
Concentration information loading... -
精製度Immunogen affinity purified
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特記事項（精製）Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab92297 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB |
追加情報
WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 28 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
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組織特異性Expressed in high levels in the prostate and many other androgen-sensitive tissues.
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関連疾患Defects in SRD5A2 are the cause of pseudovaginal perineoscrotal hypospadias (PPSH) [MIM:264600]. A form of male pseudohermaphroditism in which 46,XY males show ambiguous genitalia at birth, including perineal hypospadias and a blind perineal pouch, and develop masculinization at puberty. The name of the disorder stems from the finding of a blind-ending perineal opening resembling a vagina and a severely hypospadiac penis with the urethra opening onto the perineum.
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配列類似性Belongs to the steroid 5-alpha reductase family.
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細胞内局在Microsome membrane. Endoplasmic reticulum membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 403715 Dog
- Entrez Gene: 6716 Human
- Entrez Gene: 94224 Mouse
- Entrez Gene: 397048 Pig
- Entrez Gene: 64677 Rat
- Omim: 607306 Human
- SwissProt: P31213 Human
- SwissProt: Q3UTZ9 Mouse
see all -
別名
- 3 oxo 5 alpha steroid 4 dehydrogenase 2 antibody
- 3-oxo-5-alpha-steroid 4-dehydrogenase 2 antibody
- 5 alpha SR2 antibody
see all
画像
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Western blot - Anti-SRD5A2 antibody (ab92297)Anti-SRD5A2 antibody (ab92297) at 1 µg/ml + Human Testis lysate at 35 µg
Developed using the ECL technique.
Predicted band size: 28 kDa
プロトコール
参考文献
ab92297 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"