製品の概要

  • 製品名Anti-SRD5A2 antibody
    SRD5A2 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SRD5A2
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Pig, Cynomolgus Monkey, Rhesus monkey
  • 免疫原

    Recombinant fragment with tag: AKPSGYGKHT ESLKPAATRL PARAAWFLQE LPSFAVPA, corresponding to amino acids 29-128 of Human SRD5A2

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab61276 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 28 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
    • 組織特異性Expressed in high levels in the prostate and many other androgen-sensitive tissues.
    • 関連疾患Defects in SRD5A2 are the cause of pseudovaginal perineoscrotal hypospadias (PPSH) [MIM:264600]. A form of male pseudohermaphroditism in which 46,XY males show ambiguous genitalia at birth, including perineal hypospadias and a blind perineal pouch, and develop masculinization at puberty. The name of the disorder stems from the finding of a blind-ending perineal opening resembling a vagina and a severely hypospadiac penis with the urethra opening onto the perineum.
    • 配列類似性Belongs to the steroid 5-alpha reductase family.
    • 細胞内局在Microsome membrane. Endoplasmic reticulum membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 3 oxo 5 alpha steroid 4 dehydrogenase 2 antibody
      • 3-oxo-5-alpha-steroid 4-dehydrogenase 2 antibody
      • 5 alpha SR2 antibody
      • 5 alpha-SR2 antibody
      • 5ART2 antibody
      • e II 5 alpha reductase antibody
      • EC antibody
      • MGC138457 antibody
      • Micropenis, included antibody
      • S5A2_HUMAN antibody
      • S5AR 2 antibody
      • SR type 2 antibody
      • SRD5A2 antibody
      • Steroid 5 alpha reductase 2 antibody
      • Steroid 5-alpha-reductase 2 antibody
      • Steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) antibody
      • Type II 5-alpha reductase antibody
      see all

    Anti-SRD5A2 antibody 画像



    • Predicted band size : 28 kDa

    Anti-SRD5A2 antibody (ab61276) 使用論文

    ab61276 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab61276.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"