製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Spic
  • アプリケーション
    適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse
  • 免疫原

    A region within synthetic peptide: MTCCIDQDSL GQTFQDAIDI LIQQSAGESQ YSSENRNYMA IINPYPHVRG, corresponding to N terminal amino acids 1-50 of Mouse Spic

  • ポジティブ・コントロール
    • SP2/0 lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab49112 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/312500.
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 32 kDa (predicted molecular weight: 28 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
  • 組織特異性
    Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
  • 配列類似性
    Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AU019198 antibody
    • C76795 antibody
    • MGC40611 antibody
    • MGC80555 antibody
    • Prf antibody
    • Pu.1 related factor antibody
    • Spi C antibody
    • Spi C transcription factor antibody
    • Spi-C transcription factor (Spi-1/PU.1 related) antibody
    • spiC antibody
    • SPIC_HUMAN antibody
    • Transcription factor Spi-C antibody
    see all

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プロトコール

参考文献

ab49112 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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