Anti-Sphingomyelin Synthase 2 抗体 (ab103060)

製品の概要

  • 製品名
    Anti-Sphingomyelin Synthase 2 antibody
    Sphingomyelin Synthase 2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Sphingomyelin Synthase 2
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, between C-terminal amino acids 336-365 of Human Sphingomyelin Synthase 2.

  • ポジティブ・コントロール
    • CEM cell line, Human Brain Tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 42 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. Does not function strictly as a SM synthase. Required for cell growth.
  • 組織特異性
    Brain, heart, kidney, liver, muscle and stomach.
  • 配列類似性
    Belongs to the sphingomyelin synthase family.
  • 翻訳後修飾
    Palmitoylated on Cys-331, Cys-332, Cys-343 and Cys-348; which plays an important role in plasma membrane localization.
  • 細胞内局在
    Cell membrane. Golgi apparatus membrane. Predominantly plasma membrane, some in Golgi apparatus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC26963 antibody
    • Phosphatidylcholine:ceramide cholinephosphotransferase 2 antibody
    • SGMS 2 antibody
    • Sgms2 antibody
    • SM synthase antibody
    • SMS 2 antibody
    • SMS2 antibody
    • SMS2_HUMAN antibody
    • Sphingomyelin synthase 2 antibody
    see all

画像

  • Anti-Sphingomyelin Synthase 2 antibody (ab103060) at 1/100 dilution + CEM cell lysate at 35 µg

    Predicted band size : 42 kDa
  • IHC analysis in formalin fixed and paraffin embedded Human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining, using ab103060 at a dilution of 1/50.

参考文献

ab103060 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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