製品の概要

  • 製品名Anti-Sphingomyelin Synthase 1 antibody
    Sphingomyelin Synthase 1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Sphingomyelin Synthase 1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    A synthetic peptide corresponding to a region within internal amino acids 144 - 193 (SCFVLTTVMI SVVHERVPPK EVQPPLPDTF FDHFNRVQWA FSICEINGMI) of Human Sphingomyelin Synthase 1 (NP_671512)

  • ポジティブ・コントロール
    • HeLa cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab83856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 関連性Sphingomyelin synthase 1 is a bidirectional lipid cholinephosphotransferase capable of converting phosphatidylcholine and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and vice versa. Sphingomyelin synthase 1 is required for cell growth and is also capable of suppressing BAX-mediated apoptosis and preventing cell death in response to stimuli such as hydrogen peroxide, osmotic stress, elevated temperature and exogenously supplied sphingolipids. It may protect against cell death by reversing the stress-inducible increase in levels of proapoptotic ceramide.
  • 細胞内局在Golgi Apparatus. Multi-pass membrane protein
  • 参照データベース
  • 別名
    • MOB antibody
    • Phosphatidylcholine:ceramide cholinephosphotransferase 1 antibody
    • Protein Mob antibody
    • SGMS1 antibody
    • SMS 1 antibody
    • SMS1 antibody
    • TMEM23 antibody
    • Transmembrane protein 23 antibody
    see all

Anti-Sphingomyelin Synthase 1 antibody 画像

  • Anti-Sphingomyelin Synthase 1 antibody (ab83856) at 1 µg/ml + HeLa cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 49 kDa
    Observed band size : 49 kDa

Anti-Sphingomyelin Synthase 1 antibody (ab83856) 使用論文

This product has been referenced in:
  • Yachi R  et al. Subcellular localization of sphingomyelin revealed by two toxin-based probes in mammalian cells. Genes Cells 17:720-7 (2012). WB ; African Green Monkey . Read more (PubMed: 22747662) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"