製品の概要

  • 製品名Anti-SPDEF antibody
    SPDEF 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SPDEF
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 92-201 of Human SPDEF

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

ターゲット情報

  • 機能May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
  • 組織特異性Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells.
  • 配列類似性Belongs to the ETS family.
    Contains 1 ETS DNA-binding domain.
    Contains 1 PNT (pointed) domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • bA375E1.3 antibody
    • PDEF antibody
    • Prostate derived Ets factor antibody
    • PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR antibody
    • Prostate epithelium-specific Ets transcription factor antibody
    • Prostate specific Ets antibody
    • Prostate-derived Ets factor antibody
    • Prostate-specific Ets antibody
    • PSE antibody
    • RP11-375E1__A.3 antibody
    • SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR antibody
    • SAM pointed domain-containing Ets transcription factor antibody
    • Spdef antibody
    • SPDEF_HUMAN antibody
    see all

Anti-SPDEF antibody 画像

  • Western blot against tagged recombinant protein immunogen using ab57042 SPDEF antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

Anti-SPDEF antibody (ab57042) 使用論文

This product has been referenced in:
  • Yadav UC  et al. Aldose reductase inhibition prevents metaplasia of airway epithelial cells. PLoS One 5:e14440 (2010). WB ; Human . Read more (PubMed: 21203431) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"