製品の概要

  • 製品名Anti-SPDEF antibody
    SPDEF 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SPDEF
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide derived from the internal region of human SPDEF.

  • ポジティブ・コントロール
    • LNCAP prostate carcinoma cell lysates.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab53881 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報Peptide ELISA: Use at a concentration of 0.1 - 1 µg/ml.
    WB: Use at a concentration of 1 - 3 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 37 kDa). A weak band at 55 kDa is also detected which may be due to the glycosylated form of PDEF.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter.
    • 組織特異性Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells.
    • 配列類似性Belongs to the ETS family.
      Contains 1 ETS DNA-binding domain.
      Contains 1 PNT (pointed) domain.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • bA375E1.3 antibody
      • PDEF antibody
      • Prostate derived Ets factor antibody
      • PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR antibody
      • Prostate epithelium-specific Ets transcription factor antibody
      • Prostate specific Ets antibody
      • Prostate-derived Ets factor antibody
      • Prostate-specific Ets antibody
      • PSE antibody
      • RP11-375E1__A.3 antibody
      • SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR antibody
      • SAM pointed domain-containing Ets transcription factor antibody
      • Spdef antibody
      • SPDEF_HUMAN antibody
      see all

    Anti-SPDEF antibody (ab53881) 使用論文

    This product has been referenced in:
    • Hasnain SZ  et al. Changes in the mucosal barrier during acute and chronic Trichuris muris infection. Parasite Immunol 33:45-55 (2011). IHC ; Mouse . Read more (PubMed: 21155842) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab53881.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"