製品の概要

  • 製品名Anti-SP110 antibody
    SP110 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to SP110
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids of Human SP110.

  • ポジティブ・コントロール
    • Human spleen and tonsil tissues.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab111093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
  • 組織特異性Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 関連疾患Defects in SP110 are the cause of hepatic venoocclusive disease with immunodeficiency (VODI) [MIM:235550]. VODI is an autosomal recessive primary immunodeficiency associated with hepatic vascular occlusion and fibrosis. The immunodeficiency is characterized by severe hypogammaglobulinemia, combined T and B cell immunodeficiency, absent lymph node germinal centers, and absent tissue plasma cells.
  • 配列類似性Contains 1 bromo domain.
    Contains 1 HSR domain.
    Contains 1 PHD-type zinc finger.
    Contains 1 SAND domain.
  • 翻訳後修飾Phosphorylated (isoform 2).
  • 細胞内局在Nucleus. Found in the nuclear body.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ22835 antibody
    • IFI 41 antibody
    • IFI 75 antibody
    • IFI41 antibody
    • IFI75 antibody
    • Interferon induced protein 41 30kD antibody
    • Interferon induced protein 41 antibody
    • Interferon induced protein 41/75 antibody
    • Interferon induced protein 75 52kD antibody
    • Interferon induced protein 75 antibody
    • Interferon-induced protein 41/75 antibody
    • IPR 1 antibody
    • IPR1 antibody
    • Phosphoprotein 41 antibody
    • Phosphoprotein 75 antibody
    • SP 110 antibody
    • SP110 antibody
    • Sp110 nuclear body protein antibody
    • SP110_HUMAN antibody
    • Speckled 110 kDa antibody
    • Transcriptional coactivator Sp110 antibody
    • VODI antibody
    see all

Anti-SP110 antibody 画像

  • ab111093, at 3.75µg/ml, staining SP110 in formalin-fixed, paraffin-embedded Human Spleen tissue by Immunohistochemistry.
  • ab111093, at 3.75µg/ml, staining SP110 in formalin-fixed, paraffin-embedded Human Tonsil tissue by Immunohistochemistry.

Anti-SP110 antibody (ab111093) 使用論文

ab111093 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"