Anti-SOX6 抗体 (ab64946)
Key features and details
- Rabbit polyclonal to SOX6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-SOX6 antibody
SOX6 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SOX6 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide (Human) from the N terminus of human SOX6.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Without Mg2+ and Ca2+ -
Concentration information loading...
-
精製度
Immunogen affinity purified -
特記事項(精製)
The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab64946の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/500 - 1/1000. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa).
|
特記事項 |
---|
WB
1/500 - 1/1000. Detects a band of approximately 93 kDa (predicted molecular weight: 93 kDa). |
ターゲット情報
-
機能
Transcriptional activator. Binds specifically to the DNA sequence 5'-AACAAT-3'. Plays a key role in several developmental processes, including neurogenesis and skeleton formation. -
組織特異性
Expressed in a wide variety of tissues, most abundantly in skeletal muscle. -
配列類似性
Contains 1 HMG box DNA-binding domain. -
翻訳後修飾
Sumoylation inhibits the transcriptional activity. -
細胞内局在
Nucleus. - Information by UniProt
-
参照データベース
- Entrez Gene: 55553 Human
- Omim: 607257 Human
- SwissProt: P35712 Human
- Unigene: 368226 Human
-
別名
- HSSOX 6 antibody
- HSSOX6 antibody
- SOX 6 antibody
see all
画像
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (12)
ab64946 は 12 報の論文で使用されています。
- Song MY et al. Sirt6 reprograms myofibers to oxidative type through CREB-dependent Sox6 suppression. Nat Commun 13:1808 (2022). PubMed: 35379817
- Cao X et al. microRNA-19a-3p and microRNA-376c-3p Promote Hepatocellular Carcinoma Progression Through SOX6-Mediated Wnt/ß-Catenin Signaling Pathway. Int J Gen Med 14:89-102 (2021). PubMed: 33469348
- Zhao H et al. The circRNA_102911/miR-129-5p/SOX6 axis is involved with T lymphocyte immune function in elderly patients with laparoscopic left hepatectomy for hepatolithiasis. Exp Ther Med 21:150 (2021). PubMed: 33456517
- Zhao L et al. Circular RNA circ_0000712 regulates high glucose-induced apoptosis, inflammation, oxidative stress, and fibrosis in (DN) by targeting the miR-879-5p/SOX6 axis. Endocr J 68:1155-1164 (2021). PubMed: 33980772
- Zhou L et al. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. Elife 9:N/A (2020). PubMed: 31944179