製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SON
  • アプリケーション
    適用あり: IHC-P, WB, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence, corresponding to amino acids 1463-1598 of Human SON.

  • ポジティブ・コントロール
    • RT4, U-251 MG cell lysates; Human small intestine tissue; U-251 MG cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab121759 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

ターゲット情報

  • 機能
    Represses hepatitis B virus (HBV) core promoter activity and transcription of HBV genes and production of HBV virions. Binds to the consensus DNA sequence: 5'-GA[GT]AN[CG][AG]CC-3'. Might protect cells from apoptosis. Might be involved in pre-mRNA splicing.
  • 組織特異性
    Widely expressed, with the higher expression seen in leukocyte and heart.
  • 配列類似性
    Contains 1 DRBM (double-stranded RNA-binding) domain.
    Contains 1 G-patch domain.
  • ドメイン
    Contains 8 types of repeats which are distributed in 3 regions.
  • 細胞内局在
    Nucleus speckle. Colocalizes with the pre-mRNA splicing factor SFRS2/SC-35.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BASS1 antibody
    • Bax antagonist selected in saccharomyces 1 antibody
    • DBP-5 antibody
    • Negative regulatory element-binding protein antibody
    • NRE-binding protein antibody
    • Protein DBP-5 antibody
    • Protein SON antibody
    • SON antibody
    • SON protein antibody
    • SON_HUMAN antibody
    • SON3 antibody
    see all

画像

  • All lanes : Anti-SON antibody (ab121759) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U-251 MG cell lysate
    Lane 3 : Human Plasma lysate
    Lane 4 : Human Liver lysate
    Lane 5 : Human Tonsil lysate

    Developed using the ECL technique
  • ab121759 at 1/1200 dilution staining SON in Paraffin-embedded Human small intestine tissue by Immunohistochemistry.
  • ab121759, at 4 µg/ml, staining SON (green) in PFA-fixed, Triton X-100 permbabilized U-251 MG cells, by Immunofluorescence.

参考文献

ab121759 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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