Anti-Solute carrier family 22 member 5 抗体 (ab125416)

製品の概要

  • 製品名Anti-Solute carrier family 22 member 5 antibody
    Solute carrier family 22 member 5 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Solute carrier family 22 member 5
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 305-354 (GIVVPSTIFD PSELQDLSSK KQQSHNILDL LRTWNIRMVT IMSIMLWMTI) of Human Solute carrier family 22 member 5 (NP_003051).

  • ポジティブ・コントロール
    • OVCAR 3 lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125416 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 61 kDa (predicted molecular weight: 63 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine. Transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Also relative uptake activity ratio of carnitine to TEA is 11.3.
  • 組織特異性Strongly expressed in kidney, skeletal muscle, heart and placenta. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells.
  • 関連疾患Defects in SLC22A5 are the cause of systemic primary carnitine deficiency (CDSP) [MIM:212140]. CDSP is an autosomal recessive disorder of fatty acid oxidation caused by defective carnitine transport. Present early in life with hypoketotic hypoglycemia and acute metabolic decompensation, or later in life with skeletal myopathy or cardiomyopathy.
  • 配列類似性Belongs to the major facilitator superfamily. Organic cation transporter family.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CDSP antibody
    • High-affinity sodium-dependent carnitine cotransporter antibody
    • OCTN2 antibody
    • OCTN2VT antibody
    • Organic cation/carnitine transporter 2 antibody
    • S22A5_HUMAN antibody
    • Slc22a5 antibody
    • Solute carrier family 22 (organic cation/carnitine transporter) member 5 antibody
    • Solute carrier family 22 member 5 antibody
    see all

Anti-Solute carrier family 22 member 5 antibody 画像

  • Anti-Solute carrier family 22 member 5 antibody (ab125416) at 1 µg/ml + OVCAR 3 lysate at 10 µg

    Predicted band size : 63 kDa


  • Predicted band size : 63 kDa

Anti-Solute carrier family 22 member 5 antibody (ab125416) 使用論文

ab125416 has not yet been referenced specifically in any publications.

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