Anti-soluble IL2 Receptor gamma 抗体 [38024.11] (ab50258)

製品の概要

  • 製品名Anti-soluble IL2 Receptor gamma antibody [38024.11]
  • 製品の詳細
    Mouse monoclonal [38024.11] to soluble IL2 Receptor gamma
  • 特異性By ELISA, the antibody does not cross react with recombinant human IL2 R alpha, IL2 R beta, IL1 RI, IL1 RII, IL4 R , IL6 R, IL7 R and IL10 R.
  • アプリケーション適用あり: WB, Neutralising, Indirect ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human IL2 soluble receptor gamma.

  • 特記事項


    Monoclonal anti-Human IL2 sRg may be used to block the biological activity mediated by IL2 and for neutralization of the biological activity mediated by IL2 Rg and the detection of IL2 Rg.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)The antibody was purified from ascites fluid.
  • 一次抗体 備考Monoclonal anti-Human IL2 sRg may be used to block the biological activity mediated by IL2 and for neutralization of the biological activity mediated by IL2 Rg and the detection of IL2 Rg.
  • ポリ/モノモノクローナル
  • クローン名38024.11
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab50258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 42 kDa.

This working dilution was determined using recombinant human IL2 Rg at 100 ng/lane under non-reducing conditions.

Neutralising Use a concentration of 2 - 6 µg/ml.

This concentration was found to block 50% of the bioactivity due to 10 ng/ml recombinant human IL2 in a 3H-thymidine incorporation assay using 105 cells/ml MO7e cells.

Indirect ELISA Use a concentration of 0.5 - 1 µg/ml.

I-ELISA: Use at a concentration of 0.5 - 1 µg/ml (to a limit of 3 ng/well).

ターゲット情報

  • 関連性A common subunit for the receptors for a variety of interleukins, the gamma chain is common to the IL2, IL4, IL7, IL21 and probably also the IL13 receptors. Defects in IL2RG are the cause of X-linked severe combined immunodeficiency. The biological effects of IL2R signals are much more complex than simply mediating T-cell growth. Depending on conditions, IL2R signals may also promote cell survival, effector function, and apoptosis. These sometimes contradictory effects underscore the fact that a diversity of intracellular signalling pathways are potentially activated by IL2R. There are at least 3 components of the IL2 receptor; IL2R alpha, IL2R beta, and IL2R gamma chains.
  • 細胞内局在Membrane; single-pass type I membrane protein
  • 参照データベース
  • 別名
    • CD132 antibody
    • Cytokine receptor common gamma chain antibody
    • Gamma-C antibody
    • gammaC antibody
    • IL-2 receptor subunit gamma antibody
    • IL-2RG antibody
    • IL2R gamma chain antibody
    • IL2RG antibody
    • IMD4 antibody
    • Interleukin-2 receptor subunit gamma antibody
    • L-2R subunit gamma antibody
    • p64 antibody
    see all

Anti-soluble IL2 Receptor gamma antibody [38024.11] (ab50258) 使用論文

ab50258 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"