The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Detects a band of approximately 84 kDa (predicted molecular weight: 93 kDa).
機能Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
配列類似性Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
翻訳後修飾Phosphorylated by PKA, which inhibits activity.
細胞内局在Membrane. In intestinal epithelial cells, localizes to the ileal brush border.