製品の概要
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製品名Anti-SOCS6 antibody, prediluted
SOCS6 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to SOCS6, prediluted
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由来種Rabbit
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アプリケーション適用あり: IHC-Pmore details
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種交差性交差種: Human
交差が予測される動物種: Mouse
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免疫原
Synthetic peptide corresponding to C terminal of human SOCS6 protein.
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ポジティブ･コントロール
- A431 and HeLa cells. Placenta.
製品の特性
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製品の状態Prediluted
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保存方法Shipped at 4°C. Store at +4°C.
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バッファーPreservative: 0.1% Sodium Azide
Constituents: 1% BSA, 50mM Tris, pH 7.6 -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab53211 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| IHC-P |
追加情報
IHC-P: Ready-to-use for 30 min at RT.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM
citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM
citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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パスウェイProtein modification; protein ubiquitination.
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配列類似性Contains 1 SH2 domain.
Contains 1 SOCS box domain. -
ドメインThe SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.
- Information by UniProt
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参照データベース
- Entrez Gene: 9306 Human
- Entrez Gene: 54607 Mouse
- Omim: 605118 Human
- SwissProt: O14544 Human
- SwissProt: Q9JLY0 Mouse
- Unigene: 44439 Human
- Unigene: 476577 Mouse
- Unigene: 91920 Mouse
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別名
- CIS-4 antibody
- CIS4 antibody
- Cish4 antibody
see all
参考文献
This product has been referenced in:
- Letellier E et al. Identification of SOCS2 and SOCS6 as biomarkers in human colorectal cancer. Br J Cancer 111:726-35 (2014). IHC-P ; Human . Read more (PubMed: 25025962) »
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"