製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SOAT 1
  • アプリケーション
    適用あり: WB, IHC-P, IHC-Fr, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat, Human, Pig
    交差が予測される動物種: Cynomolgus monkey
  • 免疫原

    Synthetic peptide:

    KMSRLNRLSKSRENPEED

    , corresponding to amino acids 6/23 of Human ACAT1

  • ポジティブ・コントロール
    • Rat liver and HepG2 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab39327 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent concentration. Predicted molecular weight: 47 kDa.
IHC-P Use at an assay dependent concentration.
IHC-Fr Use a concentration of 0.4 µg/ml.
ICC/IF Use a concentration of 0.4 µg/ml.

ターゲット情報

  • 機能
    Catalyzes the formation of fatty acid-cholesterol esters. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase.
  • 配列類似性
    Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
  • 細胞内局在
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ACACT antibody
    • ACAT antibody
    • ACAT-1 antibody
    • ACAT1 antibody
    • Acyl coenzyme A cholesterol acyltransferase 1 antibody
    • Acyl-coenzyme A:cholesterol acyltransferase 1 antibody
    • Cholesterol acyltransferase 1 antibody
    • SOAT antibody
    • SOAT1 antibody
    • SOAT1_HUMAN antibody
    • STAT antibody
    • Sterol O acyltransferase 1 antibody
    • Sterol O-acyltransferase 1 antibody
    see all

画像

参考文献

This product has been referenced in:
  • Sundberg JP  et al. Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas. PLoS One 9:e113582 (2014). Read more (PubMed: 25474466) »
  • Area-Gomez E  et al. Upregulated function of mitochondria-associated ER membranes in Alzheimer disease. EMBO J 31:4106-23 (2012). Read more (PubMed: 22892566) »

See all 2 Publications for this product

レビューと Q&A

Thank you for contacting us. These two antibodies should work equally well in IHC for Human. ab53008 has not successfully been tested for other species. They do have differenct immunogenic peptides but that doesn't mean one should work better than the ...

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Thank you for your reply.

Our ab39327 is actually capable of detecting both the native a processed form of the protein. I've attached the WB image and here is the caption:

Human ACAT-1 has 550 amino acids with an estimated MW of 65 ...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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