Goat polyclonal to SNX8
, corresponding to C terminal amino acids 452-465 of Human SNX8.
Jurkat and Human Liver extracts.
GenBank Accession Number – NP_037453.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris-saline. pH 7.3
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Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Immunizing Peptide (Blocking)
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network.
Belongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Early endosome membrane. Colocalizes with retromer components.
Information by UniProt
Highly similar to MVP1 PROTEIN Saccharomyces cerevisiae antibody
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SNX8 antibody (ab5988)
ab5988 (4µg/ml) staining of paraffin embedded Human Kidney following steamed antigen retrieval with Tris/EDTA buffer pH 9 and HRP-staining shows vesicular staining in the cytoplasm of preferentially DCT epithelial cells.
has not yet been referenced specifically in any publications.
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