製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, 5mg/ml Tris, pH 7.3
  • Concentration information loading...
  • 精製度IgG fraction
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab3941 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 80 kDa (predicted molecular weight: 69 kDa).Can be blocked with Human SNX18 peptide (ab22972).

ターゲット情報

  • 機能May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
  • 配列類似性Belongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • ドメインThe PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate.
  • 細胞内局在Endomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ11997 antibody
    • FLJ32560 antibody
    • FLJ61062 antibody
    • MGC150827 antibody
    • MGC150829 antibody
    • SH3 and PX domain containing protein 3B antibody
    • SH3 and PX domain-containing protein 3B antibody
    • SH3PX2 antibody
    • SH3PXD3B antibody
    • SNAG 1 antibody
    • SNAG1 antibody
    • SNX18 antibody
    • SNX18_HUMAN antibody
    • Sorting nexin 18 antibody
    • Sorting nexin associated golgi protein 1 antibody
    • Sorting nexin-18 antibody
    • Sorting nexin-associated Golgi protein 1 antibody
    see all

Anti-SNX18 antibody 画像

Anti-SNX18 antibody (ab3941) 使用論文

ab3941 has not yet been referenced specifically in any publications.

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I am now dealing with the fast-track antibodies and am therefore going to follow up your SNX18 (ab3941) enquiries. Are you still of the opinion that an alternative splice variant exits on which the antibody might work or have you carried out western...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"