製品の概要

  • 製品名Anti-SNX18 antibody
    SNX18 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SNX18
  • アプリケーション適用あり: WB, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 382-579 of Human SNX18 (AAH60791).

  • ポジティブ・コントロール
    • A549 and HeLa cells. Cal27 xenograft tissue.

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーpH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 20% Glycerol, 1% BSA, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab111702 is purified by antigen-affinity chromatography.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab111702 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Predicted molecular weight: 69 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF 1/100 - 1/500.

ターゲット情報

  • 機能May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Stimulates the GTPase activity of DNM2. Promotes DNM2 location at the plasma membrane.
  • 配列類似性Belongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
    Contains 1 SH3 domain.
  • ドメインThe PX domain mediates interaction with membranes enriched in phosphatidylinositol-4,5-bisphosphate.
  • 細胞内局在Endomembrane system. Endosome membrane. Cell membrane. Localized at sites of endocytosis at the cell membrane. Detected on newly formed macropinosomes. Partially colocalized with clathrin and dynamin at the cell membrane. Transiently recruited to clathrin-coated pits at a late stage of clathrin-coated vesicle formation.
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ11997 antibody
    • FLJ32560 antibody
    • FLJ61062 antibody
    • MGC150827 antibody
    • MGC150829 antibody
    • SH3 and PX domain containing protein 3B antibody
    • SH3 and PX domain-containing protein 3B antibody
    • SH3PX2 antibody
    • SH3PXD3B antibody
    • SNAG 1 antibody
    • SNAG1 antibody
    • SNX18 antibody
    • SNX18_HUMAN antibody
    • Sorting nexin 18 antibody
    • Sorting nexin associated golgi protein 1 antibody
    • Sorting nexin-18 antibody
    • Sorting nexin-associated Golgi protein 1 antibody
    see all

Anti-SNX18 antibody 画像

  • Anti-SNX18 antibody (ab111702) at 1/5000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size : 69 kDa
  • ab111702 at 1/200 dilution staining SNX18 in methanol-fixed HeLa cells. Lower image shows cells co-stained with Hoechst 33342 (blue).
  • ab111702 at 1/500 dilution staining SNX18 in Formalin-fixed, paraffin-embedded cal27 xenograft tissue.

Anti-SNX18 antibody (ab111702) 使用論文

ab111702 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab111702.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"