Anti-SNTB2 抗体 (ab96295)
Key features and details
- Rabbit polyclonal to SNTB2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SNTB2 antibody -
製品の詳細
Rabbit polyclonal to SNTB2 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow, Monkey -
免疫原
Recombinant fragment, corresponding to a region within amino acids 174 - 538 of Human SNTB2
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ポジティブ・コントロール
- 293T, A431, H1299, HeLa, HepG2 and Raji cells. OVCAR3 xenograft.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96295の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 58 kDa.
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IHC-P |
1/100 - 1/500.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 58 kDa. |
IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN. -
組織特異性
Ubiquitous. Isoform 1 is the predominant isoform. Weak level of isoform 2 is present in all tested tissues, except in liver and heart where it is highly expressed. -
配列類似性
Belongs to the syntrophin family.
Contains 1 PDZ (DHR) domain.
Contains 2 PH domains.
Contains 1 SU (syntrophin unique) domain. -
ドメイン
The PH 1 domain mediates the oligomerization in a calcium dependent manner.
The PDZ domain binds to the last three or four amino acids of ion channels and receptor proteins. The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
The SU domain binds calmodulin in a calcium-dependent manner. -
翻訳後修飾
Phosphorylated. Partially dephosphorylated upon insulin stimulation. -
細胞内局在
Membrane. Cytoplasmic vesicle > secretory vesicle membrane. Cell junction. Cytoplasm > cytoskeleton. Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity). In insulinoma cell line, it is enriched in secretory granules. - Information by UniProt
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参照データベース
- Entrez Gene: 786534 Cow
- Entrez Gene: 6645 Human
- Entrez Gene: 20650 Mouse
- Entrez Gene: 689421 Rat
- Omim: 600027 Human
- SwissProt: Q13425 Human
- SwissProt: Q61235 Mouse
- Unigene: 461117 Human
see all -
別名
- Syntrophin like antibody
- 59 kDa dystrophin associated protein A1 basic component 2 antibody
- 59 kDa dystrophin-associated protein A1 basic component 2 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab96295 は論文での使用が確認できていません。