製品の概要

  • 製品名Anti-SNTB2 antibody
    SNTB2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SNTB2
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Monkey
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 174 - 538 of Human SNTB2

  • ポジティブ・コントロール
    • 293T, A431, H1299, HeLa, HepG2 and Raji cells. OVCAR3 xenograft.

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96295 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 58 kDa.
IHC-P 1/100 - 1/500.

ターゲット情報

  • 機能Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May play a role in the regulation of secretory granules via its interaction with PTPRN.
  • 組織特異性Ubiquitous. Isoform 1 is the predominant isoform. Weak level of isoform 2 is present in all tested tissues, except in liver and heart where it is highly expressed.
  • 配列類似性Belongs to the syntrophin family.
    Contains 1 PDZ (DHR) domain.
    Contains 2 PH domains.
    Contains 1 SU (syntrophin unique) domain.
  • ドメインThe PH 1 domain mediates the oligomerization in a calcium dependent manner.
    The PDZ domain binds to the last three or four amino acids of ion channels and receptor proteins. The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
    The SU domain binds calmodulin in a calcium-dependent manner.
  • 翻訳後修飾Phosphorylated. Partially dephosphorylated upon insulin stimulation.
  • 細胞内局在Membrane. Cytoplasmic vesicle > secretory vesicle membrane. Cell junction. Cytoplasm > cytoskeleton. Membrane-associated. In muscle, it is exclusively localized at the neuromuscular junction (By similarity). In insulinoma cell line, it is enriched in secretory granules.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Syntrophin like antibody
    • 59 kDa dystrophin associated protein A1 basic component 2 antibody
    • 59 kDa dystrophin-associated protein A1 basic component 2 antibody
    • Basic beta 2 syntrophin antibody
    • Beta 2 syntrophin antibody
    • Beta-2-syntrophin antibody
    • D16S2531E antibody
    • Dystrophin associated protein A1 59kD basic component 2 antibody
    • EST25263 antibody
    • SNT2B2 antibody
    • SNT3 antibody
    • Sntb2 antibody
    • SNTB2_HUMAN antibody
    • SNTL antibody
    • Syntrophin 3 antibody
    • Syntrophin beta 2 (dystrophin associated protein A1 59kDa basic component 2) antibody
    • Syntrophin-3 antibody
    • Syntrophin-like antibody
    see all

Anti-SNTB2 antibody 画像

  • Anti-SNTB2 antibody (ab96295) at 1/3000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 58 kDa
  • ab96295, at 1/500 dilution, staining SNTB2 in paraffin-embedded OVCAR3 xenograft

Anti-SNTB2 antibody (ab96295) 使用論文

ab96295 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"