製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SNTB1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 71-120 (GAGAGHPGAG GAQPPDSPAG VRTAFTDLPE QVPESISNQK RGVKVLKQEL) of Human SNTB1 (NP_066301).

  • ポジティブ・コントロール
    • ACHN cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98977 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Belongs to the syntrophin family.
    Contains 1 PDZ (DHR) domain.
    Contains 2 PH domains.
    Contains 1 SU (syntrophin unique) domain.
  • ドメイン
    The PH 1 domain mediates the oligomerization in a calcium dependent manner.
    The PDZ domain binds to the last three or four amino acids of ion channels and receptor proteins. The association with dystrophin or related proteins probably leaves the PDZ domain available to recruit proteins to the membrane.
    The SU domain binds calmodulin in a calcium-dependent manner.
  • 翻訳後修飾
    Phosphorylated by CaM-kinase II.
  • 細胞内局在
    Cell membrane, sarcolemma. Cell junction. Cytoplasm, cytoskeleton. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane and at neuromuscular junctions.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 59 DAP antibody
    • 59 kDa dystrophin associated protein A1 basic component 1 antibody
    • 59 kDa dystrophin-associated protein A1 basic component 1 antibody
    • A1B antibody
    • Beta 1 syntrophin antibody
    • Beta-1-syntrophin antibody
    • BSYN2 antibody
    • DAPA1B antibody
    • Dystrophin associated protein A1 59kDa basic component 1 antibody
    • FLJ22442 antibody
    • MGC111389 antibody
    • SNT2 antibody
    • SNT2B1 antibody
    • SNTB 1 antibody
    • Sntb1 antibody
    • SNTB1_HUMAN antibody
    • Syntrophin 2 antibody
    • Syntrophin beta 1 antibody
    • Syntrophin beta 1 (dystrophin associated protein A1 59kDa basic component 1) antibody
    • Syntrophin-2 antibody
    • Tax interaction protein 43 antibody
    • TIP 43 antibody
    • TIP-43 antibody
    see all

画像

  • Anti-SNTB1 antibody (ab98977) at 1 µg/ml + ACHN cell lysate at 10 µg

    Predicted band size : 58 kDa

プロトコール

参考文献

ab98977 has not yet been referenced specifically in any publications.

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