The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 29 kDa.
機能Involved in multiple membrane trafficking steps.
組織特異性Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas.
関連疾患Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK) [MIM:609528]. CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma.
配列類似性Belongs to the SNAP-25 family. Contains 1 t-SNARE coiled-coil homology domain.
細胞内局在Cytoplasm. Membrane. Cell junction > synapse > synaptosome. Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic.