Anti-SNAP25 Interacting Protein 抗体 (ab111343)

製品の概要

  • 製品名Anti-SNAP25 Interacting Protein antibody
  • 製品の詳細
    Rabbit polyclonal to SNAP25 Interacting Protein
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from an internal region of Human SNAP25 Interacting Protein.

  • ポジティブ・コントロール
    • HepG2 and HeLa cell extracts.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab111343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 112 kDa.

ターゲット情報

  • 機能Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
  • 組織特異性Expressed in some primary breast carcinomas where its presence is significantly associated with increased tumor size. Not detected in normal breast tissue.
  • 配列類似性Belongs to the SRCIN1 family.
  • 翻訳後修飾Tyrosine-phosphorylated in response to EGF and to cell adhesion to integrin ligands.
  • 細胞内局在Cytoplasm. Cytoplasm > cytoskeleton. Cell projection > axon. Cell projection > dendrite. Cell junction > synapse. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Localized to the perinuclear region, lamellopodia, cortical actin and actin stress fibers but not to focal adhesions. Strongly expressed in axons and dendrites of the CA1 and CA3 hippocampal regions and of the dentate gyrus. Detected in both presynapses and postsynapses and in postsynaptic density fractions.
  • Information by UniProt
  • 参照データベース
  • 別名
    • p130Cas associated protein antibody
    • p130Cas-associated protein antibody
    • P140 antibody
    • p140Cap antibody
    • SNAP-25-interacting protein antibody
    • SNIP antibody
    • SRC kinase signaling inhibitor 1 antibody
    • SRCIN1 antibody
    • SRCN1_HUMAN antibody
    see all

Anti-SNAP25 Interacting Protein antibody 画像

  • All lanes : Anti-SNAP25 Interacting Protein antibody (ab111343) at 1/500 dilution

    Lane 1 : HeLa cell extract
    Lane 2 : HepG2 cell extract
    Lane 3 : HepG2 cell extract with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 112 kDa

Anti-SNAP25 Interacting Protein antibody (ab111343) 使用論文

ab111343 has not yet been referenced specifically in any publications.

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