製品の概要
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製品名SMURF1 peptide (359-372)
SMURF1 タンパク質・ペプチド 製品一覧
製品の詳細
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由来Synthetic
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アミノ酸配列
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生物種Human
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配列PSEGSLEDEELPAQ
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領域359 to 372
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関連製品
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Corresponding Antibody
特性
Our Abpromise guarantee covers the use of ab45831 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking - Blocking peptide for Anti-SMURF1 antibody (ab40823)
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製品の状態Liquid
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
関連情報
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別名
- E3 ubiquitin-protein ligase SMURF1
- hSMURF1
- KIAA1625
see all -
機能E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Acts by mediating ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members.
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パスウェイProtein modification; protein ubiquitination.
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配列類似性Contains 1 C2 domain.
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 2 WW domains. -
翻訳後修飾Ubiquitinated by the SCF(FBXL15) complex at Lys-381 and Lys-383, leading to its degradation by the proteasome. Lys-383 is the primary ubiquitination site.
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細胞内局在Cytoplasm.
- Information by UniProt
参考文献
ab45831 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"