製品の概要

  • 製品名Anti-Smoothened antibody
    Smoothened 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Smoothened
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide against N terminal of Human Smoothened conjugated to KLH.

  • ポジティブ・コントロール
    • Human Liver & lung tissue, HuvEc cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 86 kDa.
ELISA 1/10000.
IHC-P Use a concentration of 10 µg/ml.

ターゲット情報

  • 機能G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
  • 配列類似性Belongs to the G-protein coupled receptor Fz/Smo family.
    Contains 1 FZ (frizzled) domain.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Frizzled family member 11 antibody
    • FZD11 antibody
    • Gx antibody
    • Gx protein antibody
    • Protein Gx antibody
    • SMO antibody
    • SMO_HUMAN antibody
    • SMOH antibody
    • Smoothened frizzled family receptor antibody
    • Smoothened homolog (Drosophila) antibody
    • Smoothened homolog antibody
    • Smoothened homolog precursor (SMO) (Gx protein) antibody
    • Smoothened seven transmembrane spanning receptor antibody
    see all

Anti-Smoothened antibody 画像

  • ab113438 at 10 µg/ml staining Smoothened in Human liver by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
  • ab113438 at 10 µg/ml staining Smoothened in Human lung by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
  • All lanes : Anti-Smoothened antibody (ab113438) at 1/500 dilution

    Lane 1 : Extracts from HuvEc cells
    Lane 2 : Extracts from HuvEc cells with Synthesized peptide


    Predicted band size : 86 kDa

Anti-Smoothened antibody (ab113438) 使用論文

ab113438 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab113438.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"