製品の概要

  • 製品名Anti-SMOC1 antibody
    SMOC1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SMOC1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 283-313 of Human SMOC1 (NP_071420.1, NP_001030024.1).

  • ポジティブ・コントロール
    • Mouse NIH3T3 cell line lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab116529 is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab116529 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 48 kDa.

ターゲット情報

  • 機能Plays essential roles in both eye and limb development. Probale regulator of osteoblast differentiation.
  • 組織特異性Widely expressed in many tissues with a strongest signal in ovary. No expression in spleen.
  • 関連疾患Defects in SMOC1 are the cause of ophthalmoacromelic syndrome (OAS) [MIM:206920]. A rare disorder presenting with anophthalmia or microphthalmia and limb anomalies. Limb malformations include fused 4th and 5th metacarpals and short 5th finger in hands, and olygodactyly in foot (four toes). Most patients have bilateral anophthalmia/ microphthalmia, but unilateral abnormality is also noted. Other malformations are rare, but venous or vertebral anomaly was recognized each in single cases.
  • 配列類似性Contains 2 EF-hand domains.
    Contains 1 Kazal-like domain.
    Contains 2 thyroglobulin type-1 domains.
  • 翻訳後修飾Glycosylated.
  • 細胞内局在Secreted > extracellular space > extracellular matrix > basement membrane. In or around the basement membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Secreted modular calcium-binding protein 1 antibody
    • SMOC-1 antibody
    • SMOC1 antibody
    • SMOC1_HUMAN antibody
    • SPARC-related modular calcium-binding protein 1 antibody
    see all

Anti-SMOC1 antibody 画像

  • Anti-SMOC1 antibody (ab116529) at 1/100 dilution + Mouse NIH3T3 cell line lysate at 35 µg

    Predicted band size : 48 kDa

Anti-SMOC1 antibody (ab116529) 使用論文

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"