Goat polyclonal to SMAD9
Not expected to crossreact with SMAD1 or SMAD5.
Mouse, Rat, Chicken, Dog
, corresponding to internal sequence amino acids 166-179 of Human SMAD9.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
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Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 - 2 µg/ml. Used as a reporter to detect captured recombinant SMAD9
||Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 52 kDa).
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD9 is a receptor-regulated SMAD (R-SMAD).
Expressed in heart, brain, placenta, lung, skeletal muscle, prostate, testis, ovary and small intestine. Also expressed in fetal brain, lung and kidney.
Pulmonary hypertension, primary, 2
Belongs to the dwarfin/SMAD family.
Contains 1 MH1 (MAD homology 1) domain.
Contains 1 MH2 (MAD homology 2) domain.
Phosphorylated on serine by BMP (bone morphogenetic proteins) type 1 receptor kinase.
Cytoplasm. Nucleus. In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with SMAD4.
Information by UniProt
- MAD homolog 9 antibody
- Madh6 antibody
- Mothers against decapentaplegic antibody
has not yet been referenced specifically in any publications.
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