Rabbit polyclonal to Smac / Diablo
Mouse, Rat, Human
Synthetic peptide, corresponding to amino acids 225-239 of the C-terminal region of Human Smac/ Diablo.
Storage in frost free freezers is not recommended.
Should this product contain a precipitate we recommend microcentrifugation before use.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.02% Sodium Azide
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Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 5 µg/ml.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 28.7 kDa.
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
The mature N-terminus mediates interaction with XIAP.
Mitochondrion. Released into the cytosol when cells undergo apoptosis.
Information by UniProt
- 0610041G12Rik antibody
- DBLOH_HUMAN antibody
- DBOH antibody
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