Anti-Smac / Diablo 抗体 [8H5AB2] (ab110291)

製品の概要

  • 製品名
    Anti-Smac / Diablo antibody [8H5AB2]
    Smac / Diablo 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [8H5AB2] to Smac / Diablo
  • 由来種
    Mouse
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant Smac, TIMM22 proteins

  • ポジティブ・コントロール
    • Human liver mitochondria and HepG2 cells
  • 特記事項

    This antibody clone is manufactured by Abcam.

    Product was previously marketed under the MitoSciences sub-brand.

    If you require this antibody in a particular buffer formulation or a particular conjugate for your experiments, please contact orders@abcam.com or you can find further information here.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110291 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.

ターゲット情報

  • 機能
    Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
  • 組織特異性
    Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
  • ドメイン
    The mature N-terminus mediates interaction with XIAP.
  • 細胞内局在
    Mitochondrion. Released into the cytosol when cells undergo apoptosis.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 0610041G12Rik antibody
    • DBLOH_HUMAN antibody
    • DBOH antibody
    • DFNA64 antibody
    • diablo antibody
    • Diablo homolog (Drosophila) antibody
    • Diablo homolog antibody
    • Diablo homolog mitochondrial antibody
    • Diablo IAP binding mitochondrial protein antibody
    • Diablo like protein antibody
    • DIABLO S antibody
    • Direct IAP binding protein with low pI antibody
    • Direct IAP-binding protein with low pI antibody
    • FLJ10537 antibody
    • FLJ25049 antibody
    • mitochondrial antibody
    • Mitochondrial Smac protein antibody
    • Second mitochondria derived activator of caspase antibody
    • Second mitochondria-derived activator of caspase antibody
    • SMAC 3 antibody
    • Smac antibody
    • Smac protein antibody
    • SMAC3 antibody
    see all

画像

  • All lanes : Anti-Smac / Diablo antibody [8H5AB2] (ab110291) at 1 µg/ml

    Lane 1 : Human liver mitichondria
    Lane 2 : HepG2 cells

    Predicted band size: 27 kDa

プロトコール

参考文献

ab110291 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for confirming these details and for your cooperation. The details provided enable us to closely monitor the quality of our products. I am sorry this product did not perform as stated on the datasheet and for the inconvenience this has caused...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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