Anti-Smac/Diablo 抗体 [8H5AB2] (ab110291)
Key features and details
- Mouse monoclonal [8H5AB2] to Smac/Diablo
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG2
製品の概要
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製品名
Anti-Smac/Diablo antibody [8H5AB2]
Smac/Diablo 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [8H5AB2] to Smac/Diablo -
由来種
Mouse -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Recombinant full length protein. This information is considered to be commercially sensitive.
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ポジティブ・コントロール
- Human liver mitochondria and HepG2 cells
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特記事項
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Product was previously marketed under the MitoSciences sub-brand.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. Do Not Freeze. -
バッファー
pH: 7.5
Preservative: 0.02% Sodium azide
Constituent: HEPES buffered saline -
Concentration information loading...
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精製度
Ammonium Sulphate Precipitation -
特記事項(精製)
Purity near homogeneity as judge by SDS-PAGE. The antibody was produced in-vitro using hybridomas grown in serum-free medium and then purified by biochemical fractionation. -
ポリ/モノ
モノクローナル -
クローン名
8H5AB2 -
アイソタイプ
IgG2 -
軽鎖の種類
kappa -
研究分野
関連製品
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Compatible Secondaries
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab110291の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa.
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特記事項 |
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WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. |
ターゲット情報
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機能
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP). -
組織特異性
Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. -
ドメイン
The mature N-terminus mediates interaction with XIAP. -
細胞内局在
Mitochondrion. Released into the cytosol when cells undergo apoptosis. - Information by UniProt
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参照データベース
- Entrez Gene: 56616 Human
- Omim: 605219 Human
- SwissProt: Q9NR28 Human
- Unigene: 169611 Human
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別名
- 0610041G12Rik antibody
- DBLOH_HUMAN antibody
- DBOH antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab110291 は論文での使用が確認できていません。