Anti-Slow skeletal Myosin 抗体 (ab98835)

製品の概要

  • 製品名Anti-Slow skeletal Myosin antibody
    Slow skeletal Myosin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Slow skeletal Myosin
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35 - 84 (VEFDASKIKI EFTPEQIEEF KEAFMLFDRT PKCEMKITYG QCGDVLRALG) of Human Slow skeletal Myosin (NP_000249).

  • ポジティブ・コントロール
    • COLO205 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab98835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Regulatory light chain of myosin. Does not bind calcium.
  • 関連疾患Defects in MYL3 are the cause of cardiomyopathy familial hypertrophic type 8 (CMH8) [MIM:608751]. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. CMH8 inheritance can be autosomal dominant or recessive.
    Defects in MYL3 are the cause of cardiomyopathy familial hypertrophic with mid-left ventricular chamber type 1 (MVC1) [MIM:608751]. MVC1 is a very rare variant of familial hypertrophic cardiomyopathy, characterized by mid-left ventricular chamber thickening.
  • 配列類似性Contains 3 EF-hand domains.
  • 翻訳後修飾The N-terminus is blocked.
    N-terminus is methylated by METTL11A/NTM1.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cardiac myosin light chain 1 antibody
    • CMH8 antibody
    • CMLC1 antibody
    • MLC1SB antibody
    • MLC1V antibody
    • MYL3 antibody
    • MYL3_HUMAN antibody
    • Myosin light chain 1 antibody
    • Myosin light chain 1 slow twitch muscle B ventricular isoform antibody
    • myosin light chain 3 alkali ventricular skeletal slow antibody
    • Myosin light chain 3 antibody
    • slow-twitch muscle B/ventricular isoform antibody
    • Ventricular slow twitch myosin alkali light chain antibody
    • Ventricular/slow twitch myosin alkali light chain antibody
    • VLC1 antibody
    see all

Anti-Slow skeletal Myosin antibody 画像

  • Anti-Slow skeletal Myosin antibody (ab98835) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 22 kDa

Anti-Slow skeletal Myosin antibody (ab98835) 使用論文

ab98835 has not yet been referenced specifically in any publications.

Product Wall

Thank you so much for sending these images. They will be very helpful, and I am sending them on to the lab for review.

I am also sending a free of charge vial of ab91506 on the order ***, which should arrive tomorrow. Please keep me updated a...

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Thanks for your call today and for letting us know about this problem. We really appreciate your feedback, and I will forward any data that you can send to the lab for their review.

As we discussed, I'm happy to send a replacement antibody fo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"