製品の概要

  • 製品名Anti-Slitrk1 antibody
    Slitrk1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Slitrk1
  • 特異性This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
  • アプリケーション適用あり: WB, ICC/IF, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    A 16 amino acid peptide from near the carboxy terminus of human Slitrk1.

  • ポジティブ・コントロール
    • Human brain tissue lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab67238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 88 kDa (predicted molecular weight: 78 kDa).
ICC/IF Use a concentration of 20 µg/ml.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 関連性Slitrk1 is a member of a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Tourette’s Syndrome, it is thought to play only a minor role if at all.
  • 細胞内局在Membrane; Single-pass type I membrane protein
  • 参照データベース
  • 別名
    • SLITRK1 antibody
    • FLJ54428 antibody
    • KIAA0918 antibody
    • KIAA1910 antibody
    • Leucine rich repeat containing protein 12 antibody
    • LRRC1 antibody
    • LRRC12 antibody
    • RP11-395N17.1 antibody
    • SLIT and NTRK like family, member 1 antibody
    • SLIT and NTRK-like protein 1 antibody
    • slit and trk like gene 1 antibody
    • SLITRK 1 antibody
    • TTM antibody
    • UNQ233/PRO266 antibody
    see all

Anti-Slitrk1 antibody 画像

  • Immunofluorescence of Slitrk1 in Human brain tissue with ab67238 at 20 ug/mL.

  • Immunohistochemistry of Slitrk1 in Human brain tissue with Slitrk1 antibody at 2.5 μg/mL.

  • Lane 1 : Anti-Slitrk1 antibody (ab67238) at 1 µg/ml
    Lane 2 : Anti-Slitrk1 antibody (ab67238) at 2 µg/ml

    Lane 1 : human brain tissue lysate
    Lane 2 : human brain tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 78 kDa
    Observed band size : 88 and 60 kDa (why is the actual band size different from the predicted?)

Anti-Slitrk1 antibody (ab67238) 使用論文

ab67238 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab67238.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"