製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SLIRP
  • アプリケーション
    適用あり: IHC-Fr, WBmore details
  • 種交差性
    交差種: Human
    非交差種: Mouse
  • 免疫原

    Synthetic peptide made to a C terminal region of human SLIRP.

  • ポジティブ・コントロール
    • Human liver lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab51523 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use at an assay dependent concentration.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 12 kDa (predicted molecular weight: 12 kDa).

ターゲット情報

  • 関連性
    SLIRP is a RNA binding protein that acts as a nuclear receptor corepressor. It may act by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. SLIRP binds the STR7 loop of SRA RNA. It is also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation. It contains 1 RRM (RNA recognition motif) domain. SLIRP is predominantly founs in mitochondrial with a limited role in the nucleus where it is recruited to nuclear receptor target promoters.
  • 細胞内局在
    Mitochondrial and Nuclear; Predominantly mitochondrial.
  • 参照データベース
  • 別名
    • C14orf156 antibody
    • Chromosome 14 open reading frame 156 antibody
    • DC50 antibody
    • PD04872 antibody
    • SLIRP antibody
    • SRA stem loop interacting RNA binding protein, mitochondrial antibody
    see all

画像

  • Anti-SLIRP antibody (ab51523) at 0.6 µg/ml + human liver lysate

    Predicted band size : 12 kDa
    Observed band size : 12 kDa

参考文献

This product has been referenced in:
  • Carpp LN  et al. Quantitative proteomic analysis of host-virus interactions reveals a role for Golgi brefeldin A resistance factor 1 (GBF1) in dengue infection. Mol Cell Proteomics 13:2836-54 (2014). Read more (PubMed: 24855065) »
  • Clemente P  et al. hCOA3 stabilizes cytochrome c oxidase 1 (COX1) and promotes cytochrome c oxidase assembly in human mitochondria. J Biol Chem 288:8321-31 (2013). Read more (PubMed: 23362268) »

See all 6 Publications for this product

レビューと Q&A

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunohistochemistry (Frozen sections)
Sample
Human Tissue sections (Normal skeletal muscle)
Specification
Normal skeletal muscle
Fixative
None
Permeabilization
No
Username

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投稿 Mar 29 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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