製品の概要

  • 製品名Anti-SLC9A6 antibody
    SLC9A6 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to SLC9A6
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Cow
  • 免疫原

    Recombinant fragment: YGDSTVNTEP ATSSAPRRFM GNSSEDALDR ELAFGDHELV IRGTRLVLPM DDSEPPLNLL DNTRHGPA, corresponding to amino acids 602-669 of human SLC9A6 (NP_006350) with a 26 kDa tag

  • ポジティブ・コントロール
    • SLC9A6 transfected 293T cell lysate; recombinant tagged fragment of human SLC9A6 (the immunogen).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab77110 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 74 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Electroneutral exchange of protons for Na(+) and K(+) across the early and recycling endosome membranes. Contributes to calcium homeostasis.
  • 組織特異性Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.
  • 関連疾患Defects in SLC9A6 are the cause of mental retardation syndromic X-linked Christianson type (MRXSC) [MIM:300243]; also known as MRXS-Christianson or X-linked Angelman-like syndrome. The phenotype is characterized by profound mental retardation, epilepsy, ataxia, and microcephaly, and showed phenotypic overlap with Angelman syndrome.
  • 配列類似性Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
  • 細胞内局在Endosome membrane. Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
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    • OTTHUMP00000024089 antibody
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    • RGD1563582 antibody
    • RP11-274K13.1 antibody
    • RP23-105E2.4 antibody
    • SL9A6_HUMAN antibody
    • SLC9A6 antibody
    • Sodium/hydrogen exchanger 6 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger), isoform 6 antibody
    • Solute carrier family 9 (sodium/hydrogen exchanger), member 6 antibody
    • Solute carrier family 9 member 6 antibody
    • solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 antibody
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Anti-SLC9A6 antibody 画像

  • Anti-SLC9A6 antibody (ab77110) at 1/500 dilution + Recombinant fragment of human SLC9A6 at 0.2 µg

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

    Predicted band size : 74 kDa
    Observed band size : 34 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-SLC9A6 antibody (ab77110) at 1/500 dilution

    Lane 1 : SLC9A6 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 74 kDa
    Observed band size : 65 kDa (why is the actual band size different from the predicted?)

Anti-SLC9A6 antibody (ab77110) 使用論文

ab77110 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab77110.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"