製品の概要

  • 製品名Anti-SLC7A7 antibody
    SLC7A7 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SLC7A7
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rabbit, Horse, Chicken, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 179-228 (WGTLVQDIFT YAKVLALIAV IVAGIVRLGQ GASTHFENSF EGSSFAVGDI) of Human SLC7A7 (NP_003973).

  • ポジティブ・コントロール
    • PANC1 cell lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106610 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.2 - 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes.
  • 組織特異性Highest expression in kidney and peripheral blood leukocytes. Weaker expression is observed in lung, heart, placenta, spleen, testis and small intestine. Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, retinal pigment epithelial cells, and various carcinoma cell lines, with highest expression in a colon-carcinoma cell line.
  • 関連疾患Lysinuric protein intolerance
  • 配列類似性Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
  • 細胞内局在Basolateral cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • LAT3 antibody
    • LPI antibody
    • Monocyte amino acid permease 2 antibody
    • MOP-2 antibody
    • MOP2 antibody
    • SLC7A 7 antibody
    • Slc7a7 antibody
    • Solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 antibody
    • Solute carrier family 7 member 7 antibody
    • y(+)L type amino acid transporter 1 antibody
    • y(+)L-type amino acid transporter 1 antibody
    • Y+L amino acid transporter 1 antibody
    • y+LAT-1 antibody
    • Y+LAT1 antibody
    • YLAT1_HUMAN antibody
    see all

Anti-SLC7A7 antibody 画像

  • Anti-SLC7A7 antibody (ab106610) at 1 µg/ml + PANC1 cell lysate at 10 µg

    Predicted band size : 56 kDa

Anti-SLC7A7 antibody (ab106610) 使用論文

ab106610 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"