製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SLC6A8
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    A region within synthetic peptide: CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSGGLEVPGA , corresponding to N terminal amino acids 181-230 of Human SLC6A8

  • ポジティブ・コントロール
    • MDA MB 435S cell lysate, human muscle tissue.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab62196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 71, <36 kDa (predicted molecular weight: 71 kDa).Can be blocked with SLC6A8 peptide (ab216175). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

ターゲット情報

  • 機能
    Required for the uptake of creatine in muscles and brain.
  • 組織特異性
    Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
  • 関連疾患
    Cerebral creatine deficiency syndrome 1
  • 配列類似性
    Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • SLC6A 8 antibody
    • SLC6A8 antibody
    • Creatine transporter 1 antibody
    • Creatine transporter SLC6A8 antibody
    • CRT antibody
    • CRTR antibody
    • CT 1 antibody
    • CT1 antibody
    • MGC87396 antibody
    • SC6A8_HUMAN antibody
    • Slc6a8 antibody
    • Sodium and chloride-dependent creatine transporter 1 antibody
    • Sodium- and chloride-dependent creatine transporter 1 antibody
    • Solute carrier family 6 (neurotransmitter transporter, creatine), member 8. antibody
    • Solute carrier family 6 member 8 antibody
    see all

画像

  • Anti-SLC6A8 antibody (ab62196) at 2.5 µg/ml + MDA MB 435S cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG 1/ 50,000 - 1/100,000 dilution

    Predicted band size : 71 kDa
    Observed band size : 71 kDa
    Additional bands at : <36 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human muscle tissue labelling SLC6A8 with ab62196 at 4-8µg/ml. Arrows indicate positively labelled skeletal muscle cells. Magnification: 400X.

参考文献

ab62196 has not yet been referenced specifically in any publications.

レビューと Q&A

There are currently no Customer reviews or Questions for ab62196.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録