The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 2.5 µg/ml. Detects a band of approximately 71, <36 kDa (predicted molecular weight: 71 kDa).Can be blocked with SLC6A8 peptide (ab216175). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
Use a concentration of 4 - 8 µg/ml.
機能Required for the uptake of creatine in muscles and brain.
組織特異性Predominantly expressed in skeletal muscle and kidney. Also found in brain, heart, colon, testis and prostate.
関連疾患Cerebral creatine deficiency syndrome 1
配列類似性Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily.