Anti-SLC5A3 抗体 (ab113245)
Key features and details
- Rabbit polyclonal to SLC5A3
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-SLC5A3 antibody
SLC5A3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to SLC5A3 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Synthetic peptide within Human SLC5A3 aa 221-270 (internal sequence) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
Database link: P53794 -
ポジティブ・コントロール
- Human prostate and Human uterus tissue and extracts from HUVEC cells
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.88% Sodium chloride, 50% Glycerol (glycerin, glycerine), 48% PBS -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113245の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
1/500 - 1/1000. Predicted molecular weight: 80 kDa.
|
|
IHC-P |
Use a concentration of 5 µg/ml.
|
特記事項 |
---|
WB
1/500 - 1/1000. Predicted molecular weight: 80 kDa. |
IHC-P
Use a concentration of 5 µg/ml. |
ターゲット情報
-
機能
Prevents intracellular accumulation of high concentrations of myo-inositol (an osmolyte) that result in impairment of cellular function. -
配列類似性
Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. -
細胞内局在
Membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 6526 Human
- Entrez Gene: 53881 Mouse
- Entrez Gene: 114507 Rat
- Omim: 600444 Human
- SwissProt: P53794 Human
- SwissProt: Q9JKZ2 Mouse
- Unigene: 302742 Human
- Unigene: 217354 Mouse
see all -
別名
- Na(+)/myo inositol cotransporter antibody
- Na(+)/myo-inositol cotransporter antibody
- SC5A3_HUMAN antibody
see all
画像
-
ab113245, at 5 µg/ml, staining SLC5A3 in formalin fixed, paraffin embedded Human prostate tissue.
-
ab113245, at 5 µg/ml, staining SLC5A3 in formalin fixed, paraffin embedded Human uterus tissue.
-
All lanes : Anti-SLC5A3 antibody (ab113245) at 1/500 dilution
Lane 1 : HUVEC cell extract
Lane 2 : HUVEC cell extract with synthetic peptide
Predicted band size: 80 kDa
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (3)
ab113245 は 3 報の論文で使用されています。
- Britten JL et al. Ulipristal Acetate Mediates Decreased Proteoglycan Expression Through Regulation of Nuclear Factor of Activated T-Cells (NFAT5). Reprod Sci 26:184-197 (2019). PubMed: 30567472
- Zhang X et al. The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis. Nat Commun 8:15280 (2017). WB ; Human . PubMed: 28474680
- Van Steenbergen A et al. Sodium-myoinositol cotransporter-1, SMIT1, mediates the production of reactive oxygen species induced by hyperglycemia in the heart. Sci Rep 7:41166 (2017). PubMed: 28128227