Anti-SLC5A12 抗体 (ab107749)

製品の概要

• 製品名
  Anti-SLC5A12 antibody
• 製品の詳細
  Rabbit polyclonal to SLC5A12
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Human
  
• 免疫原

  Synthetic peptide conjugated to KLH, between amino acids 583-613 from the C-terminal region of Human SLC5A12 (NP_848593.2).

• ポジティブ･コントロール
  • CEM cell line lysates.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
• バッファー
  Preservative: 0.09% Sodium Azide
  Constituents: PBS
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• 特記事項（精製）
  ab107749 is purified through a protein A column, followed by peptide affinity purification.
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Neuroscience
  • Neurotransmitter
  • Transporters
  • Other Transporters

  • Signal Transduction
  • Metabolism
  • Vitamins / Minerals

  • Metabolism
  • Pathways and Processes
  • Cofactors, Vitamins / minerals
  • Vitamins / minerals

  • Metabolism
  • Types of disease
  • Cancer

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate.
• 配列類似性
  Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
• 細胞内局在
  Apical cell membrane. Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells.

• Target information above from: UniProt accession Q1EHB4 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 159963 Human
  • Omim: 612455 Human
  • SwissProt: Q1EHB4 Human
  • Unigene: 148907 Human
• 別名
  • AI315119 antibody
  • D630015G19 antibody
  • DKFZp564G223 antibody

  • Electroneutral sodium monocarboxylate cotransporter antibody
  • Low-affinity sodium-lactate cotransporter antibody
  • MGC52019 antibody
  • RGD1311652 antibody
  • RP24-331J23.1 antibody
  • SC5AC_HUMAN antibody
  • Slc5a12 antibody
  • SMCT2 antibody
  • Sodium-coupled monocarboxylate transporter 2 antibody
  • Solute carrier family 5 member 12 antibody

  see all

プロトコール

• Western blot protocols