Anti-SLC4A8/NBC 抗体 (ab125910)
Key features and details
- Rabbit polyclonal to SLC4A8/NBC
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-SLC4A8/NBC antibody -
製品の詳細
Rabbit polyclonal to SLC4A8/NBC -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
Recombinant fragment within Human SLC4A8/NBC aa 1-255. The exact sequence is proprietary.
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ポジティブ・コントロール
- IMR32 and U87-MG whole cell lysates.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab125910の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 117 kDa.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 117 kDa. |
ターゲット情報
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機能
Mediates electroneutral sodium- and carbonate-dependent choride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity. -
組織特異性
Expressed in the pyramidal cells of the hippocampus (at protein level). Highly expressed in all major regions of the brain, spinal column and in testis, and moderate levels in trachea, thyroid and medulla region of kidney. Low expression levels observed in pancreas and kidney cortex. -
配列類似性
Belongs to the anion exchanger (TC 2.A.31) family. -
細胞内局在
Membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 9498 Human
- Entrez Gene: 59033 Mouse
- Entrez Gene: 315311 Rat
- Omim: 605024 Human
- SwissProt: Q2Y0W8 Human
- SwissProt: Q8TC60 Human
- SwissProt: Q8JZR6 Mouse
- SwissProt: Q6RVG2 Rat
see all -
別名
- Electroneutral Na(+)-driven Cl-HCO3 exchanger antibody
- Electroneutral sodium bicarbonate exchanger 1 antibody
- k-NBC3 antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab125910 は論文での使用が確認できていません。