製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SLC39A5
  • 特異性
    ab105194 is predicted not to cross-react with other ZIP family members.
  • アプリケーション
    適用あり: ICC/IF, WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    A 17 amino acid synthetic peptide from near the center of Human SLC39A5 (NP_001128667).

  • ポジティブ・コントロール
    • Human spleen tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab105194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 56 kDa.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能
    May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Plays a role in eye development. Could regulate the BMP/TGF-beta (bone morphogenetic protein/transforming growth factor-beta) signaling pathway and modulates extracellular matrix (ECM) proteins of the sclera (PubMed:24891338). Seems to play a central role in controlling organismal zinc status.
  • 組織特異性
    Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney.
  • 関連疾患
    Myopia 24, autosomal dominant
  • 配列類似性
    Belongs to the ZIP transporter (TC 2.A.5) family.
  • 翻訳後修飾
    Glycosylated.
  • 細胞内局在
    Basolateral cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • LZT Hs7 antibody
    • MGC34778 antibody
    • OTTHUMP00000211153 antibody
    • OTTHUMP00000211154 antibody
    • S39A5_HUMAN antibody
    • SLC39A5 antibody
    • solute carrier family 39 (metal ion transporter), member 5 antibody
    • Solute carrier family 39 member 5 antibody
    • Zinc transporter ZIP5 [Precursor] antibody
    • Zinc transporter ZIP5 antibody
    • ZIP 5 antibody
    • ZIP-5 antibody
    • ZIP5 antibody
    • Zrt and Irt like protein 5 antibody
    • Zrt- and Irt-like protein 5 antibody
    see all

画像

  • Immunofluorescence of SLC39A5 in Human spleen tissue with ab105194 at 20 ug/mL.
  • Immunohistochemistry of SLC39A5 in Human spleen tissue with ab105194 at 2.5 μg/mL.

  • Anti-SLC39A5 antibody (ab105194) at 1 µg/ml + Human spleen tissue lysate at 15 µg

    Predicted band size : 56 kDa

参考文献

ab105194 has not yet been referenced specifically in any publications.

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