製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to SLC39A14
  • 特異性
    At least three isoforms of SLC39A14 are known to exist; this antibody will detect all isoforms.
  • アプリケーション
    適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    16 amino acid peptide from Human SLC39A14 (NP_001128625).

  • ポジティブ・コントロール
    • Human spleen tissue lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 54 kDa.

ターゲット情報

  • 機能
    May be able to transport iron (By similarity). Acts as a zinc-influx transporter.
  • 組織特異性
    Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes.
  • 配列類似性
    Belongs to the ZIP transporter (TC 2.A.5) family.
  • 細胞内局在
    Cell membrane. Cell projection > lamellipodium. Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cig19 antibody
    • KIAA0062 antibody
    • LIV-1 subfamily of ZIP zinc transporter 4 antibody
    • LZT-Hs4 antibody
    • NET34 antibody
    • S39AE_HUMAN antibody
    • SLC39A14 antibody
    • Solute carrier family 39 (zinc transporter), member 14 antibody
    • Solute carrier family 39 member 14 antibody
    • Zinc transporter ZIP14 antibody
    • ZIP-14 antibody
    • ZIP14 antibody
    • Zrt Irt like protein 14 antibody
    • Zrt- and Irt-like protein 14 antibody
    see all

画像

  • Lane 1 : Anti-SLC39A14 antibody (ab106568) at 1 µg/ml
    Lane 2 : Anti-SLC39A14 antibody (ab106568) at 2 µg/ml

    Lane 1 : Human spleen tissue lysate
    Lane 2 : Human spleen tissue lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 54 kDa
  • Immunofluorescence of ZIP14 in Mouse Liver cells using ab106568 at 20 ug/ml.

参考文献

This product has been referenced in:
  • Wongjaikam S  et al. Restoring the impaired cardiac calcium homeostasis and cardiac function in iron overload rats by the combined deferiprone and N-acetyl cysteine. Sci Rep 7:44460 (2017). Read more (PubMed: 28287621) »
  • Tuschl K  et al. Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia. Nat Commun 7:11601 (2016). IHC . Read more (PubMed: 27231142) »

See all 2 Publications for this product

レビューと Q&A

The peptide used to raise this antibody has been taken from within the region 241-300 of Human SLC39A14, accession number NP_001128625.

As requested, I have issued a free of charge replacement with the order number XXXXX for the antibody ab106568.

To check the status of the order please contact our Customer Service team and reference this number. You will soon receive a confi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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