製品の概要

  • 製品名Anti-SLC38A1 antibody
    SLC38A1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to SLC38A1
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    A region within synthetic peptide: YLGYTSGFSL SCMVFFLIVV IYKKFQIPCI VPELNSTISA NSTNADTCTP, corresponding to internal sequence amino acids 217-266 of Human SLC38A1

  • ポジティブ・コントロール
    • HepG2 cell lysate; human kidney tissue

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab60145 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 59 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

ターゲット情報

  • 機能Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA.
  • 組織特異性Expressed in the cerebral cortex by pyramidal and GABAergic neurons, astrocytes and other non-neuronal cells (at protein level). Expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis.
  • 配列類似性Belongs to the amino acid/polyamine transporter 2 family.
  • 細胞内局在Cell membrane. Restricted to the somatodendritic compartment of neurons. Found in the cellular processes of neurons in the developing brain (By similarity).
  • Information by UniProt
  • 参照データベース
  • 別名
    • Amino acid transporter A1 antibody
    • Amino acid transporter system A1 antibody
    • ATA 1 antibody
    • ATA1 antibody
    • N-system amino acid transporter 2 antibody
    • NAT 2 antibody
    • NAT2 antibody
    • S38A1_HUMAN antibody
    • SAT 1 antibody
    • SAT1 antibody
    • SLC38A1 antibody
    • SNAT 1 antibody
    • SNAT1 antibody
    • Sodium-coupled neutral amino acid transporter 1 antibody
    • Solute carrier family 38 member 1 antibody
    • System A amino acid transporter 1 antibody
    • System N amino acid transporter 1 antibody
    see all

Anti-SLC38A1 antibody 画像

  • Anti-SLC38A1 antibody (ab60145) at 1.25 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP-conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 59 kDa
    Observed band size : 48 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human kidney tissue labelling SLC38A1 with ab60145 at 4-8µg/ml. Arrows indicate positively labelled epithelial cells of the renal tubule. Magnification: 400X.

Anti-SLC38A1 antibody (ab60145) 使用論文

This product has been referenced in:
  • Dikalova A  et al. Sodium-coupled neutral amino acid transporter 1 (SNAT1) modulates L-citrulline transport and nitric oxide (NO) signaling in piglet pulmonary arterial endothelial cells. PLoS One 9:e85730 (2014). WB ; Pig . Read more (PubMed: 24454923) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab60145.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"