製品の概要

  • 製品名Anti-SLC30A5 antibody
  • 製品の詳細
    Mouse monoclonal to SLC30A5
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-119 of Human SLC30A5

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab57590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP.
    • 組織特異性Ubiquitously expressed. Highly expressed in pancreas, liver and kidney. Expressed abundantly in insulin-containing beta cells, undetectable in other endocrine cell types including glucagon-secreting alpha cells and most acinar cells.
    • 配列類似性Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
    • 細胞内局在Golgi apparatus > trans-Golgi network membrane. Perimeter of granules, localizes to the brush border membrane of the enterocyte. Concentrated in early compartments of the secretory pathway such as COPII-coated vesicles.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp686F23142 antibody
      • FLJ12496 antibody
      • FLJ12756 antibody
      • hZTL1 antibody
      • MGC5499 antibody
      • Putative uncharacterized protein DKFZp686F23142 antibody
      • Slc30a5 antibody
      • Solute carrier family 30 (zinc transporter) member 5 antibody
      • Solute carrier family 30 (Zinc transporter), member 5 isoform CRA a antibody
      • Solute carrier family 30 member 5 antibody
      • Zinc transporter 5 antibody
      • Zinc transporter ZnT 5 antibody
      • Zinc transporter ZTL1 antibody
      • ZNT 5 antibody
      • ZnT-5 antibody
      • ZnT-like transporter 1 antibody
      • ZNT5 antibody
      • ZNT5_HUMAN antibody
      • ZNTL 1 antibody
      • ZNTL1 antibody
      • ZTL 1 antibody
      • ZTL1 antibody
      see all

    Anti-SLC30A5 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57590 SLC30A5 antibody at 1ug/ml. Predicted band size of immunogen is 39 kDa

    Anti-SLC30A5 antibody (ab57590) 使用論文

    ab57590 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57590.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"